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The hydrolysis of ATP is likely carried out by the SufBC 2 D complex, because the SufB and SufC subunits of this complex have ATPase activity (Xu and Mller, 2004

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To date, celiac disease is the condition in which the pathogenic role of an impaired barrier function is best established and where steps are being made to translate this finding to a therapeutic target

Signs withdrawal is becoming unsafe Warning signs that withdrawal may be becoming medically unsafe include rapid escalation of symptoms, particularly neurological symptoms, progressive confusion or disorientation, and inability to maintain adequate hydration or nutrition due to persistent symptoms